What's safe to delete?

I'm wondering if there is anything that's safe to delete below :

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USR :

Code (Text):

462M    /usr/bin
160M    /usr/sbin
280M    /usr/src
786M    /usr/lib
558M    /usr/lib64
59M     /usr/include
4.0K    /usr/games
4.0K    /usr/etc
513M    /usr/share
63M     /usr/libexec
1.3G    /usr/local
4.1G    /usr

VAR :

Code (Text):

4.0K    /var/preserve
20K     /var/db
4.0K    /var/adm
4.0K    /var/gopher
4.0K    /var/yp
263M    /var/log
2.0G    /var/lib
4.0K    /var/nis
8.0K    /var/empty
295M    /var/cache
19M     /var/spool
4.0K    /var/games
4.0K    /var/crash
12K     /var/tmp
4.0K    /var/opt
12K     /var/kerberos
4.0K    /var/ftp
4.0K    /var/local
2.6G    /var

RUN :

Code (Text):

0       /run/sudo
0       /run/chrony
0       /run/wpa_supplicant
8.0K    /run/blkid
0       /run/pure-ftpd
4.0K    /run/memcached
4.0K    /run/php-fpm
4.0K    /run/NetworkManager
0       /run/dbus
0       /run/plymouth
0       /run/net-snmp
0       /run/setrans
0       /run/svnserve
0       /run/sepermit
0       /run/user
0       /run/netreport
0       /run/screen
0       /run/faillock
0       /run/lock
0       /run/ppp
4.0K    /run/tuned
0       /run/console
56M     /run/log
1.3M    /run/udev
0       /run/mount
73M     /run/systemd
130M    /run

 

Even /run/log?

Already know about those links btw. I'll get the sizes of the inner folders in a bit and post it up.

 

Even /run/log?

Already know about those links btw. I'll get the sizes of the inner folders in a bit and post it up.