Wordpress - Redis Nginx Caching ?

I am assuming you're talking about with Wordpress ?

Yep these days it is recommended. Bit of background below:

Centmin Mod has a centmin.sh menu option 22 for Wordpress auto installer + WP Super Cache out of the box. This is adequately fast at the time I created this auto installer.

Cache Enable Alternative to WP Super Cache Plugin

Then came along a similar Wordpress plugin created by KeyCDN folks called, Cache Enabler. It's Nginx configuration options are virtually identical to WP Super Cache for nginx vhost configuration level. The difference is the PHP coded side of Cache Enabler WP Plugin seems alot easier to setup and less finicky than WP Super Cache when initially enabling it and the options are more simplified. As such for testing purposes, I have added optional support for Cache Enabler in centmin.sh menu option 22 ONLY for Centmin Mod 123.09beta01 builds (not 123.08 stable). For 123.08 stable Centmin Mod, to switch from WP Super Cache to Cache Enabler, follow the manual instructions outlined here instead.

Redis Nginx Level Cache + Redis Object Cache WP Plugin

However, there's an even more performant option alternative to WP Super Cache and Cache Enabler. That is provided you first have Redis server installed and configured. The Redis Nginx level cache + Redis object cache will be much faster than WP Super Cache or Cache Enabler. From testing with the Redis caching combination, it is at least 45% faster than WP Super Cache (Cache Enabler would be same as WP Super Cache as the underlying Nginx configuration level setup is virtually the same for setting up static page level caching).

 

never used wordpress multi-site so you'd be on your own there