Magento Speed Up Magento 2 Guide

1. Never Use JS Bundling
   Contrary to popular belief, bundled JavaScript files actually take longer to load as opposed to many, small, JavaScript files.

I have zero experience with Magento but have some with Joomla and Wordpress.

I have read and found that JS bundling should not be done as a general rule because it can cause latent performance and failed code execution issues, however, bundling of the common library and some other code which can be large in size while only limited portions of the library get used, can make sense. What would make more sense would be to reduce the unused code that is included in templates and modules or finds its way into sites over time as unexpunged code.
This may not make sense if your situation is different. I have experimented using different levels of bundling such as trying full bundling, finding that crashed pages or was slow, then unbundling code that needed to be called upon page load or in a certain order and leaving the rest bundled. Logic can be used to do that, however, it creates a potential problem if updates change what and in what order code is being used.

As a general rule, don't bundle. Otherwise, selectively bundle if the optimization scheme you are using provides that flexibility.

 

These people seem to have pretty good idea of optimizing servers for Magento:
magenx/Magento-nginx-config